John's wort. Doing so can lead to an excessive serotonin buildup in the brain. This can cause a condition called serotonin syndrome. Symptoms of serotonin syndrome include:. Some cases of serotonin syndrome can be life-threatening. If you're taking Effexor and experience any of these symptoms, contact your doctor as soon as possible. You should always avoid drinking or using other drugs while you're taking Effexor. These substances may decrease the benefits of the medication, or they can result in a toxic overdose.
The most common Effexor overdose effects include:. To reduce your risk of overdose, your doctor will only prescribe you the lowest possible dose in the smallest quantity. Children and adolescents up to age 25 may experience increased suicidal thoughts and behaviors when taking antidepressant medications.
The danger is greatest the first few months of treatment or when changing the dose. Though this warning is true for all antidepressants, taking Effexor may increase your risk even more. A major study found that Effexor was associated with a higher risk of both completed and attempted suicide compared with other antidepressants, including Celexa citalopram , Prozac fluoxetine , and Prothiaden dothiepin.
If you are having suicidal thoughts, contact the National Suicide Prevention Lifeline at for support and assistance from a trained counselor. If you or a loved one are in immediate danger, call For more mental health resources, see our National Helpline Database. Stopping Effexor abruptly may result in one of more of the following withdrawal symptoms :.
It's important to not stop taking Effexor on your own. If you and your doctor decide it's best for you to stop Effexor, they can provide you with a tapering strategy to minimize any withdrawal symptoms.
Before prescribing Effexor, your doctor will take a thorough medical history. Even so, it's important for you to play an active role in your care. Be sure to share every detail of your health history, regardless of whether or not you think it's important. Overall, Effexor is a well-tolerated medication that has helped many people cope with a variety of mental health conditions. You deserve to get well. The good news is that if Effexor doesn't help, there are lots of other options to try.
Dealing with racing thoughts? Always feeling tired? Our guide offers strategies to help you or your loved one live better with bipolar disorder. Sign up for our newsletter and get it free. Shelton RC. Serotonin and norepinephrine reuptake inhibitors. Handb Exp Pharmacol. Food and Drug Administration. Effexor label. Updated December Seizure induced by a therapeutic dose of Venlafaxine ER: A case report.
J Psychiatr Pract. Do antidepressants increase the risk of mania and bipolar disorder in people with depression? A retrospective electronic case register cohort study. BMJ Open. Suicidality in children and adolescents being treated with antidepressant medications. Published February 5, Risk of suicide during treatment with venlafaxine, citalopram, fluoxetine, and dothiepin: retrospective cohort study.
Your Privacy Rights. To change or withdraw your consent choices for VerywellMind. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page. This marks the first antidepressant approved for panic disorder since Panic disorder affects 2.
It is characterized by recurrent, unexpected panic attacks; i. In one study, less than 20 percent of sufferers were diagnosed and treated to remission. Because panic disorder is under recognized and not always treated to remission, patients are likely to experience a chronic and cyclical course of symptoms. Panic disorder may be associated with conditions such as depression or other anxiety disorders.
Antidepressants increased the risk of suicidal thinking and behavior suicidality in short-term studies in children and adolescents with Major Depressive Disorder MDD and other psychiatric disorders. Patients who are started on therapy should be observed closely for clinical worsening, suicidality, or unusual changes in behavior.
Families and caregivers should be advised of the need for close observation and communication with the prescriber. Patients should be observed closely for clinical worsening and suicidality, especially at the beginning of drug therapy, or at the time of increases or decreases in dose. Anxiety, agitation, panic attacks, insomnia, irritability, hostility, impulsivity, akathisia, hypomania, and mania have been reported and may represent precursors to emerging suicidality.
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