With donations from people like. Do I Need Another Endoscopy? Question I underwent an endoscopic exam about 1 year ago and was diagnosed with gastroesophageal reflux disease GERD. This information is in no way intended to replace the guidance of your doctor. All Rights Reserved. About GERD. What is GERD?
H2 Blockers. Unwanted actions H2 antagonists have been so widely used that many side effects are attributed to them, although not necessarily caused by them. Safety has not been proven in pregnant women and the drugs appear in breast milk. Use H2 antagonists are effective in most cases of heartburn that do not respond to life-style measures.
Summary Histamine H2 blockers inhibit the action of histamine on gastric H2 receptors thereby decreasing gastric acidity. Share this page. Share on facebook. Share on twitter. Share on linkedin. Share on email. Share on print. Topics of this article. H2 blockers are easily available over-the-counter at most pharmacies, making them an easy solution for heartburn relief, indigestion, or acid indigestion.
H2 blocker medications are most often taken orally with the first meal of the day. It may take only minutes for the H2 blocker to start working, and the benefits may up to 24 hours after dosage. Healthcare providers may prescribe H2 blockers alongside other medications during treatment for peptic ulcers.
While some may experience mild to moderate symptoms associated with H2 blockers, there may be safety issues relating to long-term treatment.
High doses of cimetidine may cause reversible impotence or gynecomastia and may interact with many other medical drug prescriptions. Long-term use of H2 blockers for acid suppression may include the risk of proliferation of gastric flora and hyperplasia which may result in gastric malignancy.
Treatment options for GERD vary by case and severity of symptoms. Some patients may experience relief from changes in lifestyle and eating habits. This may include discovering what foods to limit or avoid , or changing sleeping positions to keep the head elevated. Medication therapy , such as H2 blockers or proton pump inhibitors, limits the production of acid in the stomach and is commonly used to treat acid reflux, ulcers, heartburn, and inflammation.
While taking medication can relieve symptoms, they are sometimes accompanied by side effects, or may not be available to patients who are breastfeeding or have underlying liver issues. Surgical options for GERD are available for patients that do not wish to take acid suppression medications for extended periods or as a life long treatment.
A transoral incisionless fundoplication — TIF procedure reconstructs the antireflux valve. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.
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This content does not have an Arabic version. If you are prescribed or buy an H2 blocker, read this to be sure you are safe to take it.
Note : taking some H2 blockers can affect how well other medicines work. You should also tell your doctor if you take theophylline, a medicine commonly used to treat asthma or chronic obstructive pulmonary disease COPD. You should consult your doctor if your symptoms worsen, or if you experience any of the following problems which can indicate a serious gut disorder:.
If you are taking antacids you should not take them at the same time as you take your other medication, including H2 blockers. This is because antacids can affect how well other medication is absorbed. If you think you have had a side-effect to one of your medicines you can report this on the Yellow Card Scheme. You can do this online at www. The Yellow Card Scheme is used to make pharmacists, doctors and nurses aware of any new side-effects that medicines or any other healthcare products may have caused.
If you wish to report a side-effect, you will need to provide basic information about:. Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management ; NICE Clinical Guideline Sept - last updated October Br J Gen Pract. I have also recently developed Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions.
Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.
In this series. In this article What are H2 blockers? How do H2 blockers work? What conditions are they used to treat?
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